replicationforkcollapse

由MFalk著作·2018·被引用36次—Collapsedreplicationforksthusrepresentthedominanttypeofdamageincryopreservedcells(DMSOortrehalose+DMSO),inwhichothereffects ...,,由CMKondratick著作·2021·被引用39次—Prolongedstallingofreplicationincellsleadstoforkcollapse,whichinvolvesdisassemblyofthereplisome,forkreversaland/orbreakagegeneratingDNA ...,由DCortez著作·2015·被引用257次—Robustmechanismsensurethatstalled...

參考資訊如下
Chromatin architecture changes and DNA replication fork ...

由 M Falk 著作 · 2018 · 被引用 36 次 — Collapsed replication forks thus represent the dominant type of damage in cryopreserved cells (DMSO or trehalose + DMSO), in which other effects ...

DNA replication stress

Making choices

由 CM Kondratick 著作 · 2021 · 被引用 39 次 — Prolonged stalling of replication in cells leads to fork collapse, which involves disassembly of the replisome, fork reversal and/or breakage generating DNA ...

Preventing Replication Fork Collapse to Maintain Genome ...

由 D Cortez 著作 · 2015 · 被引用 257 次 — Robust mechanisms ensure that stalled forks remain stable and capable of either resuming DNA synthesis or being rescued by converging forks.

Replication fork instability and the consequences of ...

由 JL Alexander 著作 · 2016 · 被引用 107 次 — Obstructions to replication fork progression cause fork stalling and increase the likelihood of fork collapse and breakage. Although stalled forks can resume ...

Stalled DNA Replication Fork

However, prolonged RF stalling leads to DNA damage; alternatively, the fork may collapse if Rad53 (Cds1 in fission yeast, or Chk1 in metazoa) is absent, and ...